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  🧠 Neuropsychiatric Lupus (Neuro-Lupus): When Lupus Affects the Brain, Nerves & Mind Systemic Lupus Erythematosus (SLE) is known as a disease that can affect any organ system in the body. When lupus begins to impact the brain, spinal cord, or peripheral nerves, it is called Neuropsychiatric Lupus or Neuropsychiatric Systemic Lupus Erythematosus (NPSLE). This is one of the most complex — and often misunderstood — forms of lupus. It can affect thinking, mood, memory, movement, circulation, and even perception of reality. And for many patients… it is invisible. 🧬 What Is Neuro-Lupus? Neuro-lupus occurs when immune-mediated inflammation damages parts of the nervous system. This may involve: Brain tissue Blood vessels supplying the brain Spinal cord Peripheral nerves Autonomic nervous system Symptoms may be mild and vague… or severe and life-threatening. ⚠️ Common Symptoms of Neuropsychiatric Lupus Cognitive & Emotional Symptoms Often called...